Chris Burghes will join the Blue Cross as chief executive in June.
Sally de la Bedoyere will retire at the end of June after five years at the pet charity, and Burghes will join the organisation from 1 June.
The accounts for the year ending 31 December 2018 put the Blue Cross’ income at £39.5m and its spending at £38.1m.
Burghes was previously the chief executive of the Royal Free Charity which is the charitable arm of the Royal Free London NHS Foundation Trust.
He said: “I am excited to be joining Blue Cross which has grown into one of the largest and best loved pet welfare charities in the country. It is a wonderful time to join the charity and lead the organisation on the next stage of its strategy, building on its renowned reputation for providing unique and holistic services to pets and their owners.
“I have been incredibly impressed with what I have seen so far, which is a credit to the trustees, staff and volunteers at Blue Cross. The passion and dedication of everyone is second to none. I truly believe that pets change lives and I’ll be proud to lead the charity and help more pets and their owners in the future.”
Bedoyere led the charity through significant growth, with its income increasing by nearly 20 per cent during her tenure.
She said: “I have thoroughly enjoyed every minute of my time leading Blue Cross in an ever-changing environment of pet welfare and developing a strategy to deliver the greatest impact to improve the lives of pets and people.
“By adapting the ways our services work and taking advantage of digital developments we have been able to reach more animals in need, help more pet owners in crisis and spread the message of best pet welfare. I would like to thank all my teams and look forward to following the journey of Blue Cross into the future.”