Youth charities and other organisations have been given £40m from the Department for Culture Media and Sport's Youth Investment Fund.
DCMS said that the money is set to benefit 300,000 young people, providing new opportunities for them to get involved in their communities, support their personal development and get the skills they need to enter the workplace.
DCMS said the Youth Investment Fund will be shared by 86 youth organisations across East London, Liverpool City Region, West Midlands, Tees Valley and Sunderland, Bristol & Somerset and Eastern Counties over the next three years.
The £40m fund was announced last September with the government and BIG each contributing £20m to the pot.
Organisations that have received the funding include Liverpool charity the Youth Federation, which received £750,000 to improve youth provision across Wirral, Halton and St Helens.
Cambridgeshire LGBT charity the Kite Trust will receive £193,000 to create four safe spaces for 600 people to receive advice and support on issues such as isolation.
Other organisations who have recieved funding include Ministry of Stories, Royal Society for Bind Children, Suffolk YMCA and the What Centre.
New Philanthropy Capital and the Centre for Youth Impact will work alongside each of the 86 organisations to evaluate the impact of their work with young people.
Tracey Crouch, minister for civil society, said: "This investment from the government and National Lottery players will have a transformational effect on the lives of some of our most disadvantaged young people. It will help thousands who might otherwise have gone under the radar flourish. Local voluntary and community youth organisations already do so much fantastic work and this £40m will enrich the lives of many more young people throughout England."
Dawn Austwick, chief executive of the Big Lottery Fund, said: "The Youth Investment Fund is a welcome boost for the many great community organisations that work with young people locally. Money raised by National Lottery players creates opportunities for young people to build on their talents and strengths and the Youth Investment Fund is an important part of the jigsaw for the youth sector."
The £40m Youth Investment Fund was announced by Prime Minister Theresa May in September last year.
The full list of charities and organisations to benefit from the funding can be found here.